Tyr^em1Mhwn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tyr^em1Mhwn
• Name: tyrosinase; endonuclease-mediated mutation 1, Matthew H Wilson
• MGI ID: MGI:7343861
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^em1Mhwn page

Mutation origin

• Strain of Origin: C57BL/6NHsd

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 1 produced a null allele. (J:301626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 382 strains or lines available

References

• Original: J:301626 Beckermann TM, et al., CRISPR/Cas9 engineering of albino cystinuria Type A mice. Genesis. 2020 May;58(5):e23357
• All: 1 reference(s)