Kcnk18^em1Rchen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnk18^em1Rchen
• Name: potassium channel, subfamily K, member 18; endonuclease-mediated mutation 1, Rongqing Chen
• MGI ID: MGI:7341776
• Synonyms: Tresk^-
• Gene: Kcnk18 Location: Chr19:59208080-59225802 bp, + strand Genetic Position: Chr19, 54.63 cM
• Alliance: Kcnk18^em1Rchen page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2 and 3. (J:329126)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk18 Mutation: 18 strains or lines available

References

• Original: J:329126 Huang W, et al., TRESK channel contributes to depolarization-induced shunting inhibition and modulates epileptic seizures. Cell Rep. 2021 Jul 20;36(3):109404
• All: 1 reference(s)