Aldh1a2^tm1.2Mbp
Targeted Allele Detail

Summary

• Symbol: Aldh1a2^tm1.2Mbp
• Name: aldehyde dehydrogenase family 1, subfamily A2; targeted mutation 1.2, Mouse Biology Program, UC Davis
• MGI ID: MGI:7327624
• Gene: Aldh1a2 Location: Chr9:71123071-71203525 bp, + strand Genetic Position: Chr9, 39.85 cM
• Alliance: Aldh1a2^tm1.2Mbp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324715
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector inserted into intron 3 an FRT-flanked neomycin resistance cassette with a 3' UTR and into intron 4 an additional loxP site. Flp-mediated recombination removed the selection cassette and exon 4. (J:324715)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aldh1a2 Mutation: 36 strains or lines available

References

• Original: J:324715 Topping T, et al., Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis. Front Endocrinol (Lausanne). 2022;13:871225
• All: 1 reference(s)