Igf2bp3^em1Drao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igf2bp3^em1Drao
• Name: insulin-like growth factor 2 mRNA binding protein 3; endonuclease-mediated mutation 1, Dinesh S Rao
• MGI ID: MGI:7327568
• Synonyms: Igf2bp3^f
• Gene: Igf2bp3 Location: Chr6:49062157-49191891 bp, - strand Genetic Position: Chr6, 23.82 cM, cytoband B2.3
• Alliance: Igf2bp3^em1Drao page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking exon 2. (J:327031)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2bp3 Mutation: 34 strains or lines available

References

• Original: J:327031 Tran TM, et al., The RNA-binding protein IGF2BP3 is critical for MLL-AF4-mediated leukemogenesis. Leukemia. 2022 Jan;36(1):68-79
• All: 1 reference(s)