Zng1^em1Epsk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zng1^em1Epsk
• Name: Zn regulated GTPase metalloprotein activator 1; endonuclease-mediated mutation 1, Eric P Skaar
• MGI ID: MGI:7327087
• Synonyms: Zng1^-
• Gene: Zng1 Location: Chr19:24897280-24938974 bp, - strand Genetic Position: Chr19, 19.86 cM
• Alliance: Zng1^em1Epsk page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRIPSR/Cas9 technology targeting exon 1 generated a deletion spanning the start codon and 50 amino acids within exon 1, including the CPELVPI motif. (J:325966)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zng1 Mutation: 25 strains or lines available

References

• Original: J:325966 Weiss A, et al., Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis. Cell. 2022 Jun 9;185(12):2148-2163.e27
• All: 1 reference(s)