Klf14^em1Mmcc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klf14^em1Mmcc
• Name: Kruppel-like transcription factor 14; endonuclease-mediated mutation 1, Mark I McCarthy
• MGI ID: MGI:7316489
• Synonyms: Klf14^fl
• Gene: Klf14 Location: Chr6:30932956-30935925 bp, - strand Genetic Position: Chr6, 12.54 cM
• Alliance: Klf14^em1Mmcc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRIDPR-targeting floxed the single exon. (J:260827)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf14 Mutation: 25 strains or lines available

References

• Original: J:260827 Small KS, et al., Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nat Genet. 2018 Apr;50(4):572-580
• All: 2 reference(s)