Tdo2^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tdo2^em2Gpt
• Name: tryptophan 2,3-dioxygenase; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7314950
• Gene: Tdo2 Location: Chr3:81865719-81883035 bp, - strand Genetic Position: Chr3, 35.97 cM
• Alliance: Tdo2^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exons 3 through 8 generated a null allele. (J:325478)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tdo2 Mutation: 38 strains or lines available

References

• Original: J:325478 Li S, et al., A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice. Transgenic Res. 2021 Dec;30(6):781-797
• All: 1 reference(s)