Hemgn^em1Xguo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hemgn^em1Xguo
• Name: hemogen; endonuclease-mediated mutation 1, Xiang Guo
• MGI ID: MGI:7314490
• Gene: Hemgn Location: Chr4:46393989-46404183 bp, - strand Genetic Position: Chr4, 24.73 cM
• Alliance: Hemgn^em1Xguo page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting generated a null allele. (J:326018)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hemgn Mutation: 30 strains or lines available

References

• Original: J:326018 Guo X, et al., Hemogen/BRG1 cooperativity modulates promoter and enhancer activation during erythropoiesis. Blood. 2022 Jun 16;139(24):3532-3545
• All: 1 reference(s)