2010003K11Rik^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: 2010003K11Rik^em1Cya
• Name: RIKEN cDNA 2010003K11 gene; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7310331
• Synonyms: Faci^-
• Gene: 2010003K11Rik Location: Chr19:4546816-4548611 bp, - strand Genetic Position: Chr19, 4.07 cM, cytoband A
• Alliance: 2010003K11Rik^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 3000 bp deletion in the 2010003K11Rik gene coding sequence. RT-PCR analysis confirmed the absence of mRNA in the jejunum and the liver. (J:326325)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 2010003K11Rik Mutation: 1 strain or line available

References

• Original: J:326325 Cheng Y, et al., FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity. Cell Mol Gastroenterol Hepatol. 2022 Jan 28
• All: 1 reference(s)