Lag3^{tm1(LAG3)Smoc}
Targeted Allele Detail

Summary

• Symbol: Lag3^{tm1(LAG3)Smoc}
• Name: lymphocyte-activation gene 3; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7290765
• Synonyms: Lag3^{tm1(hLAG3)Smoc}
• Gene: Lag3 Location: Chr6:124881324-124888668 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Lag3^{tm1(LAG3)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Lag3^{tm1(LAG3)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LAG3 (3902)

  Lag3	(MGI:106588)

• Mutation details: The endogenous mouse Lag3 gene exon 1-7 was replaced by human LAG3 gene extracellular region by homologous recombination. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lag3 Mutation: 41 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)