Igs2^{em7(CAG-ACHE)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igs2^{em7(CAG-ACHE)Smoc}
• Name: intergenic site 2; endonuclease-mediated mutation 7, Shanghai Model Organisms Center
• MGI ID: MGI:7290391
• Synonyms: Igs2^{em1(CAG-LSL-ACHE-WPRE-pA)Smoc}
• Gene: Igs2 Location: Chr11:3195460-3195497 bp Genetic Position: Chr11, Syntenic
• Alliance: Igs2^{em7(CAG-ACHE)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Igs2^{em7(CAG-ACHE)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACHE (43)

  Ache	(MGI:87876)

• Mutation details: These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs2 Mutation: 72 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)