Igs2 Other Genome Feature Detail

Summary

• Symbol
  Igs2
• Name
  intergenic site 2
• Synonyms
  H11, Hipp11, Iis2

• Feature Type
  unclassified other genome feature
• IDs
  MGI:5461148

Location &
Maps

• Sequence Map
  Chr11:3195460-3195497 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• Personal communications (Evgeny Kvon) and J:352731: GRCm39: chr11:3195460-3195497 (GRCm38: chr11:3245460-3245497); insertion results in 38 bp deletion.

• Genetic Map
  Chromosome 11, Syntenic

Strain
Comparison

• SNPs within 2kb
  69 from dbSNP Build 142

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from 7 alleles in 4 genetic backgrounds
  19 phenotypes from multigenic genotypes
  247 phenotype references
  

• All Mutations and Alleles
  217
• Endonuclease-mediated
  173
• Targeted
  43
• Transgenic
  1
• Find Mice (IMSR)
  72 strains or lines available

Mice homozygous for knock-in alleles exhibit no abnormal phenotype.

References

• Summaries
  All 249

  Diseases 2

  Phenotypes 247
• Earliest
  J:166047 Hippenmeyer S, et al., Genetic mosaic dissection of lis1 and ndel1 in neuronal migration. Neuron. 2010 Nov 18;68(4):695-709
• Latest
  J:365589 Perelli L, et al., Evolutionary fingerprints of epithelial-to-mesenchymal transition. Nature. 2025 Apr;640(8060):1083-1092