Ctla4^{em1(CTLA4)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctla4^{em1(CTLA4)Smoc}
• Name: cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7289187
• Synonyms: Ctla4^{em1(hCTLA4)Smoc}
• Gene: Ctla4 Location: Chr1:60948184-60954991 bp, + strand Genetic Position: Chr1, 30.58 cM, cytoband C
• Alliance: Ctla4^{em1(CTLA4)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Ctla4^{em1(CTLA4)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CTLA4 (1493)

  Ctla4

  (MGI:88556)

• Mutation details: The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctla4 Mutation: 53 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)