Ccr5^{tm1(CCR5)Smoc}
Targeted Allele Detail

Summary

• Symbol: Ccr5^{tm1(CCR5)Smoc}
• Name: C-C motif chemokine receptor 5; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7288741
• Synonyms: Ccr5^{tm1(hCCR5)Smoc}
• Gene: Ccr5 Location: Chr9:123921557-123934153 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr5^{tm1(CCR5)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Ccr5^{tm1(CCR5)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CCR5 (1234)

  Ccr5	(MGI:107182)

• The endogenous mouse Ccr5 gene was replaced by human CCR5 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr5 Mutation: 29 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)