Otud1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Otud1^em1Cya
• Name: OTU domain containing 1; endonuclease-mediated mutation 1, Cyagen
• MGI ID: MGI:7266883
• Synonyms: Otud1^em1Cgen, Otud1^em1cyagen
• Gene: Otud1 Location: Chr2:19662563-19665394 bp, + strand Genetic Position: Chr2, 13.78 cM
• Alliance: Otud1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 was selected as the target site. No further details available. (J:324167)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Otud1 Mutation: 15 strains or lines available

References

• Original: J:324167 Zhang L, et al., Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome. PLoS Pathog. 2018 May;14(5):e1007067
• All: 4 reference(s)