Skp1^em1Keish
Endonuclease-mediated Allele Detail

Summary

• Symbol: Skp1^em1Keish
• Name: S-phase kinase-associated protein 1; endonuclease-mediated mutation 1, Kei-ichiro Ishiguro
• MGI ID: MGI:7261295
• Synonyms: Skp1^{3xFLAG-HA knock-in}
• Gene: Skp1 Location: Chr11:52122822-52137685 bp, + strand Genetic Position: Chr11, 31.86 cM
• Alliance: Skp1^em1Keish page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted a triple FLAG-HA epitope tag into exon 6. A neomycin resistance cassette was inserted downstream of the 3'UTR. (J:322322)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Skp1 Mutation: 18 strains or lines available

References

• Original: J:322322 Tanno N, et al., FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. iScience. 2022 Apr 15;25(4):104008
• All: 1 reference(s)