Rnf186^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf186^em1Gpt
• Name: ring finger protein 186; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7258494
• Synonyms: Rnf186^em1Cflox, RNF186^F
• Gene: Rnf186 Location: Chr4:138694430-138695676 bp, + strand Genetic Position: Chr4, 70.57 cM, cytoband D3
• Alliance: Rnf186^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites flanking the first exon. (J:317480)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf186 Mutation: 11 strains or lines available

References

• Original: J:317480 Ji Y, et al., The role and mechanism of action of RNF186 in colorectal cancer through negative regulation of NF-kappaB. Cell Signal. 2020 Nov;75:109764
• All: 2 reference(s)