Fcgr1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fcgr1^em1Smoc
• Name: Fc receptor, IgG, high affinity I; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7258110
• Gene: Fcgr1 Location: Chr3:96190225-96201285 bp, - strand Genetic Position: Chr3, 41.72 cM
• Alliance: Fcgr1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the coding region. (J:322181)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fcgr1 Mutation: 35 strains or lines available

References

• Original: J:322181 Jiang L, et al., Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice. Front Immunol. 2022;13:824008
• All: 1 reference(s)