Tnfsf15^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnfsf15^em1Cya
• Name: tumor necrosis factor (ligand) superfamily, member 15; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7258098
• Synonyms: Tnfsf15^em1Cgen
• Gene: Tnfsf15 Location: Chr4:63642837-63663296 bp, - strand Genetic Position: Chr4, 34.06 cM
• Alliance: Tnfsf15^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: CRISPR/cas9 mediated recombination using guide RNA targeting exons 2-3 created a mutation in this gene. (J:322241)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfsf15 Mutation: 20 strains or lines available

References

• Original: J:322241 Li J, et al., Tumor necrosis factor ligand-related molecule 1A maintains blood-retinal barrier via modulating SHP-1-Src-VE-cadherin signaling in diabetic retinopathy. FASEB J. 2021 Nov;35(11):e22008
• All: 1 reference(s)