Trio^tm1.1Mzhu
Targeted Allele Detail

Summary

• Symbol: Trio^tm1.1Mzhu
• Name: triple functional domain (PTPRF interacting); targeted mutation 1.1, Min-Sheng Zhu
• MGI ID: MGI:7257782
• Gene: Trio Location: Chr15:27730737-28025934 bp, - strand Genetic Position: Chr15, 10.4 cM
• Alliance: Trio^tm1.1Mzhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:321518
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trio Mutation: 134 strains or lines available

References

• Original: J:321518 Sun X, et al., Dysfunction of Trio GEF1 involves in excitatory/inhibitory imbalance and autism-like behaviors through regulation of interneuron migration. Mol Psychiatry. 2021 Dec;26(12):7621-7640
• All: 1 reference(s)