Cpa3^{em1(HBEGF)Lira}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cpa3^{em1(HBEGF)Lira}
• Name: carboxypeptidase A3, mast cell; endonuclease-mediated mutation 1, Sergio A Lira
• MGI ID: MGI:6887769
• Synonyms: Cpa3^DTR-tdTomato
• Gene: Cpa3 Location: Chr3:20269784-20296345 bp, - strand Genetic Position: Chr3, 6.25 cM
• Alliance: Cpa3^{em1(HBEGF)Lira} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Cpa3^{em1(HBEGF)Lira} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HBEGF (1839)

  Hbegf

  (MGI:96070)

• Mutation details: CRISPR-targeting inserted into the 3 prime UTR of exon 11 a human diphtheria toxin receptor gene (HBEGF), IRES and tdTomato reporter gene. (J:317124)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpa3 Mutation: 28 strains or lines available

References

• Original: J:317124 Ahrends T, et al., Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections. Cell. 2021 Nov 11;184(23):5715-5727.e12
• All: 1 reference(s)