Smarca4^em1Jgwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Smarca4^em1Jgwu
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; endonuclease-mediated mutation 1, Jiang Wu
• MGI ID: MGI:6886074
• Synonyms: Brg1-SA
• Gene: Smarca4 Location: Chr9:21527465-21615526 bp, + strand Genetic Position: Chr9, 7.84 cM
• Alliance: Smarca4^em1Jgwu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the mutation that results in the amino acid substitution of serine with alanine at position 1382 (S1382A). (J:321420)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarca4 Mutation: 110 strains or lines available

References

• Original: J:321420 Kim B, et al., Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation. Cell Rep. 2021 Jul 13;36(2):109357
• All: 1 reference(s)