Glb1^em1Wbmg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Glb1^em1Wbmg
• Name: galactosidase, beta 1; endonuclease-mediated mutation 1, Wolfgang Baumgaertner
• MGI ID: MGI:6871015
• Gene: Glb1 Location: Chr9:114230146-114303447 bp, + strand Genetic Position: Chr9, 64.4 cM
• Alliance: Glb1^em1Wbmg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• TALEN-targeting inserted a lacZ reporter gene into exon 15, deleting 6 bp. (J:320314)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glb1 Mutation: 50 strains or lines available

References

• Original: J:320314 Eikelberg D, et al., Axonopathy and Reduction of Membrane Resistance: Key Features in a New Murine Model of Human GM1-Gangliosidosis. J Clin Med. 2020;9(4)
• All: 2 reference(s)