Gdf11^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gdf11^em1Cya
• Name: growth differentiation factor 11; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6870535
• Synonyms: Gdf11^em1Cgen, GDF11^fl
• Gene: Gdf11 Location: Chr10:128718164-128727587 bp, - strand Genetic Position: Chr10, 77.18 cM, cytoband D3
• Alliance: Gdf11^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:318750)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gdf11 Mutation: 18 strains or lines available

References

• Original: J:318750 Sun J, et al., Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy. Aging Cell. 2022 Jan;21(1):e13532
• All: 1 reference(s)