Ddx20^tm1.1Htak
Targeted Allele Detail

Summary

• Symbol: Ddx20^tm1.1Htak
• Name: DEAD box helicase 20; targeted mutation 1.1, Hirohide Takebayashi
• MGI ID: MGI:6865674
• Synonyms: Ddx20^flox
• Gene: Ddx20 Location: Chr3:105585586-105594890 bp, - strand Genetic Position: Chr3, 46.43 cM, cytoband F3
• Alliance: Ddx20^tm1.1Htak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319560
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 2. Flp-mediated recombination removed the selection cassette inserted downstream of exon 2. (J:319560)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx20 Mutation: 33 strains or lines available

References

• Original: J:319560 Simankova A, et al., Ddx20, DEAD box helicase 20, is essential for the differentiation of oligodendrocyte and maintenance of myelin gene expression. Glia. 2021;69(11):2559-2574
• All: 2 reference(s)