Celf1^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Celf1^tm1Ics
• Name: CUGBP, Elav-like family member 1; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6861776
• Synonyms: Celf1^cKO, Celf1^flox
• Gene: Celf1 Location: Chr2:90770727-90849842 bp, + strand Genetic Position: Chr2, 50.44 cM
• Alliance: Celf1^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261250
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 5. (J:261250)

Expression

In Mice Carrying this Mutation:

7 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celf1 Mutation: 147 strains or lines available

References

• Original: J:261250 Siddam AD, et al., The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet. 2018 Mar;14(3):e1007278
• All: 3 reference(s)