Mettl14^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl14^em1Cya
• Name: methyltransferase 14, N6-adenosine-methyltransferase subunit; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6856811
• Synonyms: Mettl14-, Mettl14^em1Cgen
• Gene: Mettl14 Location: Chr3:123161944-123179639 bp, - strand Genetic Position: Chr3, 53.96 cM
• Alliance: Mettl14^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology was used to delete exons 7-10. (J:317709)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mettl14 Mutation: 37 strains or lines available

References

• Original: J:317709 Pang P, et al., Mettl14 Attenuates Cardiac Ischemia/Reperfusion Injury by Regulating Wnt1/beta-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:762853
• All: 5 reference(s)