Mapkapk5^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mapkapk5^em1Smoc
• Name: MAP kinase-activated protein kinase 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6842313
• Synonyms: Prak^flox
• Gene: Mapkapk5 Location: Chr5:121663114-121683955 bp, - strand Genetic Position: Chr5, 61.84 cM, cytoband F
• Alliance: Mapkapk5^em1Smoc page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting produced a floxed allele. (J:312674)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapkapk5 Mutation: 31 strains or lines available

References

• Original: J:312674 Mi L, et al., PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation. Front Immunol. 2021;12:618561
• All: 2 reference(s)