Actmap^em1Nki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Actmap^em1Nki
• Name: actin maturation protease; endonuclease-mediated mutation 1, The Netherlands Cancer Institute
• MGI ID: MGI:6831070
• Gene: Actmap Location: Chr7:26895206-26909611 bp, + strand Genetic Position: Chr7, 15.84 cM
• Alliance: Actmap^em1Nki page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted 577 bp encompassing exon 4. Immunoblot analysis confirmed absence of protein in intestine and kidney. (J:331923)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Actmap Mutation: 56 strains or lines available

References

• Original: J:331923 Haahr P, et al., Actin maturation requires the ACTMAP/C19orf54 protease. Science. 2022 Sep 30;377(6614):1533-1537
• All: 1 reference(s)