Rnf111^em1Litt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf111^em1Litt
• Name: ring finger 111; endonuclease-mediated mutation 1, Dan R Littman
• MGI ID: MGI:6818629
• Synonyms: Arkadia^fl
• Gene: Rnf111 Location: Chr9:70332706-70411007 bp, - strand Genetic Position: Chr9, 39.53 cM
• Alliance: Rnf111^em1Litt page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 genome editing is used to insert loxP sites on either side of exon 13. (J:314220)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf111 Mutation: 323 strains or lines available

References

• Original: J:314220 Xu H, et al., Arkadia-SKI/SnoN signaling differentially regulates TGF-beta-induced iTreg and Th17 cell differentiation. J Exp Med. 2021 Nov 1;218(11)
• All: 1 reference(s)