Clstn3^tm1Tymo
Targeted Allele Detail

Summary

• Symbol: Clstn3^tm1Tymo
• Name: calsyntenin 3; targeted mutation 1, Toru Yamamoto
• MGI ID: MGI:6780685
• Gene: Clstn3 Location: Chr6:124407715-124441743 bp, - strand Genetic Position: Chr6, 59.15 cM
• Alliance: Clstn3^tm1Tymo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297152
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exons 1 through 3 with a neomycin resistance cassette. (J:297152)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clstn3 Mutation: 65 strains or lines available

References

• Original: J:297152 Gotoh N, et al., Amyloidogenic processing of amyloid beta protein precursor (APP) is enhanced in the brains of alcadein alpha-deficient mice. J Biol Chem. 2020 Jul 10;295(28):9650-9662
• All: 3 reference(s)