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Tent5cem2Hncs
Endonuclease-mediated Allele Detail
Summary
Symbol: Tent5cem2Hncs
Name: terminal nucleotidyltransferase 5C; endonuclease-mediated mutation 2, Chunsheng Han
MGI ID: MGI:6761748
Synonyms: FAM46C-1
Gene: Tent5c  Location: Chr3:100375373-100396508 bp, - strand  Genetic Position: Chr3, 43.71 cM
Alliance: Tent5cem2Hncs page
Mutation
origin
Strain of Origin:  C57BL/6J x DBA
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR-targeting generated a single-base deletion at +232 bp of the coding sequence. (J:277640)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tent5c Mutation:  21 strains or lines available
References
Original:  J:277640 Zheng C, et al., Non-canonical RNA polyadenylation polymerase FAM46C is essential for fastening sperm head and flagellum in mice. Biol Reprod. 2019 Jun 1;100(6):1673-1685
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory