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Taar1em1Ejc
Endonuclease-mediated Allele Detail
Summary
Symbol: Taar1em1Ejc
Name: trace amine-associated receptor 1; endonuclease-mediated mutation 1, Elissa Chesler
MGI ID: MGI:6761312
Gene: Taar1  Location: Chr10:23796304-23797302 bp, + strand  Genetic Position: Chr10, 11.39 cM, cytoband A3
Alliance: Taar1em1Ejc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Hypomorph)
Mutation:    Single point mutation
 
Mutation detailsThis CRISPR/Cas9 mediated C to A point substitution in C57BL/6J results in a p.P77T mutation identical to that of the m1J spontaneous point mutation that occurred in DBA/2J (J:310042)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Taar1 Mutation:  22 strains or lines available
References
Original:  J:310042 Phillips TJ, et al., Confirmation of a causal Taar1Allelic variant in addiction-relevant methamphetamine behaviors. Front Psychiatry. 2021;12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory