Nthl1^tm1Rhe
Targeted Allele Detail

Summary

• Symbol: Nthl1^tm1Rhe
• Name: nth (endonuclease III)-like 1 (E.coli); targeted mutation 1, Rhoderick H Elder
• MGI ID: MGI:6758244
• Gene: Nthl1 Location: Chr17:24851656-24857812 bp, + strand Genetic Position: Chr17, 12.42 cM, cytoband A3
• Alliance: Nthl1^tm1Rhe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290906
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced 63 bp in exon 4 with a neomycin resistance cassette. (J:290906)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nthl1 Mutation: 13 strains or lines available

References

• Original: J:290906 Elder RH, et al., Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts. J Biol Chem. 2002 Dec 27;277(52):50487-90
• All: 3 reference(s)