Tyr^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tyr^{em1(cre/ERT2)Smoc}
• Name: tyrosinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6758073
• Synonyms: Tyr-CreERT2, Tyr^{em1(CreERT2)Smoc}
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tyr^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tyr (MGI:98880)

• Mutation details: This tamoxifen-inducible tyrosine-CreERT2 allele was generated by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of the Tyr (tyrosine) gene. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tyr (mouse) Summary of all recombinase alleles driven by Tyr. Alliance mouse Tyr gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 375 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)