Gt(ROSA)26Sor^{tm2(UBC-Ifi202b)Ashn}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(UBC-Ifi202b)Ashn}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Annette Schurmann
• MGI ID: MGI:6739796
• Synonyms: Tg(Ifi202b)
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(UBC-Ifi202b)Ashn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261575
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(UBC-Ifi202b)Ashn} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ifi202b (MGI:1347083)

• Gt(ROSA)26Sor^{tm2(UBC-Ifi202b)Ashn} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  UBC (7316)

  Ubc	(MGI:98889)

• Mutation details: The targeting construct inserted into the locus a human promoter driving experession of a Myc-tagged Ifi202b cDNA. (J:261575)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:261575 Stadion M, et al., Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans. Diabetologia. 2018 May;61(5):1167-1179
• All: 1 reference(s)