Nrbf2^tm1.1Jzg
Targeted Allele Detail

Summary

• Symbol: Nrbf2^tm1.1Jzg
• Name: nuclear receptor binding factor 2; targeted mutation 1.1, Jianhua Zhang
• MGI ID: MGI:6729888
• Synonyms: Nrbf2^loxP
• Gene: Nrbf2 Location: Chr10:67102463-67121076 bp, - strand Genetic Position: Chr10, 34.89 cM
• Alliance: Nrbf2^tm1.1Jzg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297962
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site upstream of exon 1 and an FRT-flanked neomycin resistance cassette with a 3' loxP site downstream of exon 1. Flp-mediated recombination removed the selection cassette and left exon 1 floxed. (J:297962)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrbf2 Mutation: 16 strains or lines available

References

• Original: J:297962 Ouyang X, et al., Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory. Lab Invest. 2020 Sep;100(9):1238-1251
• All: 1 reference(s)