Gpr174^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr174^em1Smoc
• Name: G protein-coupled receptor 174; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6729887
• Gene: Gpr174 Location: ChrX:106299484-106340375 bp, + strand Genetic Position: ChrX, 47.48 cM
• Alliance: Gpr174^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 5. (J:301163)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gpr174 Mutation: 6 strains or lines available

References

• Original: J:301163 Zhu M, et al., The increased marginal zone B cells attenuates early inflammatory responses during sepsis in Gpr174 deficient mice. Int Immunopharmacol. 2020 Apr;81:106034
• All: 1 reference(s)