Ms4a3^{tm1(cre/ERT2)Smoc}
Targeted Allele Detail

Summary

• Symbol: Ms4a3^{tm1(cre/ERT2)Smoc}
• Name: membrane-spanning 4-domains, subfamily A, member 3; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6726594
• Synonyms: Ms4a3^CreERT2
• Gene: Ms4a3 Location: Chr19:11606863-11618215 bp, - strand Genetic Position: Chr19, 8.47 cM, cytoband B
• Alliance: Ms4a3^{tm1(cre/ERT2)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:284702
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Ms4a3^{tm1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ms4a3 (MGI:2158468)

• Mutation details: A Ires-CreERT2 gene fusion was inserted into t into the 3' un-translated region (3'UTR) of the Ms4a3 gene by by homologous recombination in ES cells. (J:284702)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ms4a3 (mouse) Summary of all recombinase alleles driven by Ms4a3. Comparative matrix view of recombinase activities Alliance mouse Ms4a3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ms4a3 Mutation: 17 strains or lines available

References

• Original: J:284702 Liu Z, et al., Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells. Cell. 2019 Sep 5;178(6):1509-1525.e19
• All: 2 reference(s)