Trap1a^tm1.1Yliu
Targeted Allele Detail

Summary

• Symbol: Trap1a^tm1.1Yliu
• Name: tumor rejection antigen P1A; targeted mutation 1.1, Yang Liu
• MGI ID: MGI:6726262
• Gene: Trap1a Location: ChrX:138234432-138238918 bp, + strand Genetic Position: ChrX, 61.35 cM
• Alliance: Trap1a^tm1.1Yliu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306349
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct introduced a loxP site upstream of exon 1 and a floxed neomycin resistance cassette downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. (J:306349)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trap1a Mutation: 6 strains or lines available

References

• Original: J:306349 Li CS, et al., Trap1a is an X-linked and cell-intrinsic regulator of thymocyte development. Cell Mol Immunol. 2017 Aug;14(8):685-692
• All: 1 reference(s)