Hilpda^tm1Xen
Targeted Allele Detail

Summary

• Symbol: Hilpda^tm1Xen
• Name: hypoxia inducible lipid droplet associated; targeted mutation 1, Taconic Biosciences
• MGI ID: MGI:6724249
• Gene: Hilpda Location: Chr6:29272487-29275445 bp, + strand Genetic Position: Chr6, 12.36 cM
• Alliance: Hilpda^tm1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301866
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced coding region in exon 2 with a luciferase reporter gene and a floxed neomycin resistance cassette. (J:301866)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hilpda Mutation: 10 strains or lines available

References

• Original: J:301866 VandeKopple MJ, et al., Stress-responsive HILPDA is necessary for thermoregulation during fasting. J Endocrinol. 2017 Oct;235(1):27-38
• All: 1 reference(s)