Mest^tm1.1Rkz
Targeted Allele Detail

Summary

• Symbol: Mest^tm1.1Rkz
• Name: mesoderm specific transcript; targeted mutation 1.1, Robert Koza
• MGI ID: MGI:6724085
• Synonyms: Mest^pFL
• Gene: Mest Location: Chr6:30723546-30748464 bp, + strand Genetic Position: Chr6, 12.53 cM, cytoband B1
• Alliance: Mest^tm1.1Rkz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:245106
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector contains a loxP-flanked neomycin cassette introduced to intron 2 and a loxP site in intron 3. Cre-mediated recombination removed the floxed neo cassette leaving exon 3 floxed. (J:245106)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mest Mutation: 29 strains or lines available

References

• Original: J:245106 Anunciado-Koza RP, et al., Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest). PLoS One. 2017;12(6):e0179879
• All: 1 reference(s)