Ppm1a^tm1Xhf
Targeted Allele Detail

Summary

• Symbol: Ppm1a^tm1Xhf
• Name: protein phosphatase 1A, magnesium dependent, alpha isoform; targeted mutation 1, Xin-Hua Feng
• MGI ID: MGI:6723814
• Gene: Ppm1a Location: Chr12:72804231-72846593 bp, + strand Genetic Position: Chr12, 30.26 cM, cytoband C3
• Alliance: Ppm1a^tm1Xhf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259873
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• A null allele was generated. (J:259873)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppm1a Mutation: 23 strains or lines available

References

• Original: J:259873 Xiang W, et al., PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1. Sci Adv. 2016 Jul;2(7):e1501889
• All: 2 reference(s)