Dnah9^tm1Hmd
Targeted Allele Detail

Summary

• Symbol: Dnah9^tm1Hmd
• Name: dynein, axonemal, heavy chain 9; targeted mutation 1, Hiroshi Hamada
• MGI ID: MGI:6720870
• Synonyms: Dnah9^Venus
• Gene: Dnah9 Location: Chr11:65722150-66059379 bp, - strand Genetic Position: Chr11, 40.53 cM
• Alliance: Dnah9^tm1Hmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301033
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The Venus fluorescent protein gene, preceded by sequence for (Gly₄Ser)₃ linker peptide, was inserted immediately upstream of the stop codon to create a Dnah9-Venus fusion protein gene. A loxP site flanked neomycin resistance gene cassette was inserted downstream. (J:301033)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dnah9 Mutation: 234 strains or lines available

References

• Original: J:301033 Ide T, et al., CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components. PLoS Genet. 2020 Dec;16(12):e1009232
• All: 1 reference(s)