Ambn^em1(cre)Mlp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ambn^em1(cre)Mlp
• Name: ameloblastin; endonuclease-mediated mutation 1, Michael L Paine
• MGI ID: MGI:6696099
• Synonyms: Ambn-IRESCre
• Gene: Ambn Location: Chr5:88603850-88616390 bp, + strand Genetic Position: Chr5, 43.63 cM
• Alliance: Ambn^em1(cre)Mlp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Ambn^em1(cre)Mlp expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ambn (MGI:104655)

• Mutation details: CRISPR/cas9 genome editing is used to introduce IRES-Cre recombinase sequence followed by a polyA signal after the stop codon at the end of exon 11 (3' UTR). (J:94077)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ambn (mouse) Summary of all recombinase alleles driven by Ambn. Alliance mouse Ambn gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ambn Mutation: 32 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)