Map3k5^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Map3k5^{tm1c(EUCOMM)Hmgu}
• Name: mitogen-activated protein kinase kinase kinase 5; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6507755
• Synonyms: ASK1^flox
• Gene: Map3k5 Location: Chr10:19810218-20018499 bp, + strand Genetic Position: Chr10, 9.35 cM
• Alliance: Map3k5^{tm1c(EUCOMM)Hmgu} page
• IMPC: Map3k5 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280567
• Parent Cell Line: JM8A1.N3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Map3k5 Mutation: 63 strains or lines available

References

• Original: J:280567 Challa TD, et al., Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis. EMBO Mol Med. 2019 Oct;11(10):e10124
• All: 2 reference(s)