Nenf^tm1Nit
Targeted Allele Detail

Summary

• Symbol: Nenf^tm1Nit
• Name: neuron derived neurotrophic factor; targeted mutation 1, Nobuyuki Itoh
• MGI ID: MGI:6507395
• Synonyms: neudesin^-
• Gene: Nenf Location: Chr1:191038984-191050328 bp, - strand Genetic Position: Chr1, 96.28 cM, cytoband H6
• Alliance: Nenf^tm1Nit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301956
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin selection cassette replaced exons 2 and 3. RT-PCR analysis showed that no detectable mRNA is expressed in white adipose tissue. (J:301956)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nenf Mutation: 6 strains or lines available

References

• Original: J:301956 Ohta H, et al., Deletion of the Neurotrophic Factor neudesin Prevents Diet-induced Obesity by Increased Sympathetic Activity. Sci Rep. 2015 May 8;5:10049
• All: 1 reference(s)