Ikbkg^tm2Dln
Targeted Allele Detail

Summary

• Symbol: Ikbkg^tm2Dln
• Name: inhibitor of kappaB kinase gamma; targeted mutation 2, David L Nelson
• MGI ID: MGI:6506615
• Gene: Ikbkg Location: ChrX:73436896-73497460 bp, + strand Genetic Position: ChrX, 38.0 cM
• Alliance: Ikbkg^tm2Dln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutations: Insertion, Single point mutation
• Mutation details: This allele harbors an A>G substitution homologous to a reported case ("IP-TMC") of human incontinentia pigmenti (NM_001099857.3:c.1259A>G/p.(*420Trpext*27)). This allele reproduces the associated stop codon alteration, but it does not introduce an extension of 27 amino acids as in humans. Instead, it adds, 5' in-frame, an immediate HA tag. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikbkg Mutation: 15 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)