Igs2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Igs2^em1Smoc
• Name: intergenic site 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6501025
• Synonyms: H11-rRFP, Igs2^{em1(CAG-RSR-tdTomato)Smoc}
• Gene: Igs2 Location: Chr11:3195460-3195497 bp Genetic Position: Chr11, Syntenic
• Alliance: Igs2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: This allele contains a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette inserted into the locus via CRISPR/Cas-mediated homologous recombination. (J:299217)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs2 Mutation: 69 strains or lines available

References

• Original: J:299217 Liu X, et al., Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells. Cell Rep. 2019 Jul 30;28(5):1346-1361.e4
• All: 5 reference(s)