Trim16^tm1Gmma
Targeted Allele Detail

Summary

• Symbol: Trim16^tm1Gmma
• Name: tripartite motif-containing 16; targeted mutation 1, Glenn M Marshall
• MGI ID: MGI:6479657
• Synonyms: TRIM16^flox
• Gene: Trim16 Location: Chr11:62711034-62733774 bp, + strand Genetic Position: Chr11, 38.75 cM
• Alliance: Trim16^tm1Gmma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290272
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1 to 6 were flanked by loxP sites. In addition, a PGK-neomycin was inserted downstream of exon 6 before the second loxP site. (J:290272)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim16 Mutation: 28 strains or lines available

References

• Original: J:290272 Sutton SK, et al., Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis. J Cancer Res Clin Oncol. 2019 Sep;145(9):2241-2250
• All: 1 reference(s)